International Consortium to study Developmental Origins of Diseases (19 October 2020)

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Published 19 October 2020

Developmental Origins of Health and Disease (DOHaD) emphasizes the role of prenatal and perinatal exposures, such as undernutrition, in determining the development of human diseases in adulthood. The Healthy Life Trajectories Initiative (HeLTI) is an international consortium set up by the Canadian Institutes of Health Research (CIHR) with its counterparts in India, South Africa, and China (in collaboration with WHO) to conduct DOHaD trials in 4 countries.

The goal of the study, Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally—Early Interventions to Support Trajectories for Healthy Life in India (EINSTEIN): a Healthy Life Trajectories Initiative (HeLTI) Study, (published in BMJ Open) is to generate evidence to inform international policy and decision-making for the improvement of health and the prevention of non-communicable diseases. Dr. Saumyadipta Pyne is a co-PI of the consortium. (Image courtesy: HeLTI)