My research has covered a range of topics, including human-computer interaction, information visualization, bioinformatics, universal usability, security, privacy, and public policy implications of computing systems. I have published more than 25 peer-reviewed journal and conference papers and two book chapters. I am currently working on the development of highly-interactive, user-centered systems for finding and exploring biomedical datasets, with specific applications ranging from basic research data to electronic health records. Earlier efforts included NSF-funded projects in computer security in introductory computer science classes and computational thinking. In addition to my research experience in computer science education, I have taught and developed several courses at both undergraduate and graduate levels, including Introductory Computer Science, Introduction to Algorithms, Information Visualization, Advanced Web Development, and Human-Computer Interaction. I am a reviewer for several journals, including Information Visualization, ACM Transactions on Human Computer Interaction, Interacting with Computers, Risk Analysis, and Advances in Bioinformatics. I have also served on program committees for several conferences, including the IEEE Information Visualization Symposium (2007-2009), the ACM Symposium on Usable Privacy and Security (2009-2010), Advanced Visual Interfaces (2010), and the Security and Privacy in Medical and Home-Care Systems Workshop (2009-2010). I have been a member of the Executive Committee of the Association of Computing Machinery's US Public Policy Committee (USACM) since 2004, and I am co-author of Research Methods in Human-Computer Interaction (Wiley, 2010).
Zhou Yuan, Sean Finan, Jeremy Warner, Guergana Savova, Harry Hochheiser. Interactive Exploration of Longitudinal Cancer Patient Histories Extracted from Clinical Text. JCO Cancer Clinical Informatics May 2020 DOI: 10.1200/CCI.19.00115 PMID: 32383981 PMCID In progress
Chu JH, Zang W, Vukmirovic M, Yan X, Adams T, Deluliis G, Hu B, Mihaljinec A, Schupp JC, Becich MJ, Hochheiser H, Gibson KF, Chen ES, Morris A, Leader JK, Wisniewski SR, Zhang Y, Sciurba FC, Collman RG, Sandhaus R, Herzog EL, Patterson KC, Sauler M, Strange C, Kaminski N, GRADS Investigators. Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency. Thorax 2020 Dec 10;thoraxjnl-2019-214301. doi:10.1136/thoraxjnl-2019-214301. PMCID: 33303696 PMCID: In Progress
Grizzle AJ, Hines LE, Malone DC, Kravchenko O, Hochheiser H, Boyce RD. Testing the face validity and inter-rater agreement of a simple approach to drug-drug interaction evidence assessment. J Biomed Inform. 2020 Jan;101:103355. doi: 10.1016/j.jbi.2019.103355. Epub 2019 Dec 12. PMID: 31838211; DOI: 10.1016/j.jbi.2019.103355.
Warner JL, Dymshyts D, Reich CG, Gurley MJ, Hochheiser H, Moldwin ZH, Belenkaya R, Williams AE, Yang PC. HemOnc: A New Standard Vocabulary for Chemotherapy Regimen Representation in the OMOP Common Data Model. J Biomed Inform. 2019 Jun 22. doi: 10.1016/j.jbi.2019.103239 PMID:31238109; PMCID: PMC6697579 [Available on 2020-08-01].
Cai C, Cooper GF, Lu KN, Ma X, Xu S, Zhao Z, Chen X, Xue Y, Lee AV, Clark N, Chen V, Lu S, Chen L, Yu L, Hochheiser HS, Jiang X, Wang JQ, Lu X. Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference. PLOS Comput Biol, 2019 Jul 15(7):e1007088. doi: 10.1371/journal.pcbi.1007088. [Epub ahead of print] PMID: 31276486; PMCID: PMC6650088.
Trivedi G, Hong C, Dadashzadeh ER, Handzel RM, Hochheiser H, Visweswaran S. Identifying incidental findings from radiology reports of trauma patients: An evaluation of automated feature representation methods. International Journal of Medical Informatics. 2019 Sept 129; 81-7. DOI: 10.1016/j.ijmedinf.2019.05.021 PMID:31445293 PMCID: PMC 6717529
Wu DTY, Chen AT, Manning JD, Levy-Fix G, Backonja U, Borland D, Caban JJ, Dowding DW, Hochheiser H, Kagan V, Kandaswamy S, Kumar M, Nunez A, Pan E, Gotz D. Evaluating visual analytics for health informatics applications: a systematic review from the American Medical Informatics Association Visual Analytics Working Group Task Force on Evaluation. J Am Med Inform Assoc. 2019 Apr 1;26(4):314-323. doi: 10.1093/jamia/ocy90. PubMed PMID: 30840080.
King A, Cooper GF, Clermont G, Hochheiser H, Hauskrecht M, Sittig DF, Visweswaran S. Using machine learning to selectively highlight patient information. Journal of Biomedical Informatics. 2019; Oct 29;100:103327. DOI: 1016/j.jbi.2019.103329. PMID: 31676461; PMCID: PMC6932869 [Available on 2020-12-01].
Schnetz MP, Hochheiser HS, Danks DJ, Landsittel DP, Vogt KM, Ibinson JW, Whitehurst SL, McDermott SP, Duque MG, Kaynar AM. The triple variable index combines information generated over time from common monitoring variables to identify patients expressing distinct patterns of intraoperative physiology. BMC Med Res Methodol. 2019 Jan 14;19(1):17. doi: 10.1186/s12874-019-0660-9. PMID: 30642260. PMCID: PMC6332613.
King AJ, Cooper GF, Hochheiser H, Clermont G, Hausrecht M, Visweswaran S. Using Machine Learning to Predict the Information Seeking Behavior of Clinicians Using an Electronic Medical Record System. AMIA Annual Symp Proc. 2018 Dec 5;2018:673-682. eCollection 2018. PubMed PMID: 30815109. PMCID: PMC6371238.
Ogoe HA, Asamani JA, Hochheiser H, Douglas GP. Assessing Ghana's eHealth Workforce: implications for planning and training. Human Resources for Health. 2018 Nov 27;16(1):65. doi: https://doi.org/10.1186/s12960-018-0330-8. PMID: 30482223. PMCID: PMC6260724.
Markham H, Hochheiser H, Kuntoro K, Notobroto HB. Exploring Midwives' Need and Intention to Adopt Electronic Integrated Antenatal Care. Perspect Health Inf Manag. 2018 Jan 1;15(Winter):1e. eCollection 2018 Winter. PMID: 29618961. PMCID: PMC5869442.
Trivedi G, Pham P, Chapman WW, Hwa R, Wiebe J, Hochheiser H. NLPReViz: an interactive tool for natural language processing on clinical text. J Am Med Inform Assoc. 2017 Jul 22. doi: 10.1093/jamia/ocx070. [Epub ahead of print] PMID: 29016825.
King AJ, Hochheiser H, Visweswaran S, Clermont G, Cooper GF. Eye-tracking for Clinical Decision Support: A Method to Capture Automatically What Physicians Are Viewing in the EMR. AMIA Jt Summits Transl Sci Proc. 2017 Jul 26;2017:512-521. eCollection 2017. PMID: 28815151. PMCID: PMC5543363.
Calvitti A, Hochheiser H, Ashfaq S, Bell K, Chen Y, El Kareh R, Gabuzda MT, Liu L, Mortensen S, Pandey B, Rick S, Street RL, Weibel N, Weir C, Agha Z. Physician activity during outpatient visits and subjective workload. J. Biomed. Inf. 2017 May;69:135-149. doi: 10.1016/j.jbi.2017.03.011. Epub 2017 Mar 18. PubMed PMID: 28323144.
Savova GK, Tseytlin E, Finan S, Castine M, Miller T, Medvedeva O, Harris D, Hochheiser H, Lin C, Chavan G, Jacobson RS. DeepPhe: A Natural Language Processing System for Extracting Cancer Phenotypes from Clinical Records. Cancer Res. 2017 Nov 1;77(21):e115-e118. doi: 10.1158/0008-5472.CAN-17-0615. PMID:29092954. PMCID: PMC5690492 [Available on 2018-11-01].
Mungall CJ, McMurry JA, Köhler S, Balhoff JP, Borromeo C, Brush M, Carbon S, Conlin T, Dunn N, Engelstad M, Foster E, Gourdine JP, Jacobson JOB, Keith D, Laraway B, Lewis SE, NguyenXuan J, Shefchek K, Vasilevsky N, Yuan Z, Washington N, Hochheiser H, Groza T, Smedley D, Robinson PN, Haendel MA. The Monarch Initiative: An Integrative Data and Analytic Platform Connecting Phenotypes to Genotypes across Species. Nucleic Acids Res. 2017 Jan 4;45(D1):D712-D722. doi: 10.1093/nar/gkw1128. Epub 2016 Nov 29. PubMed PMID: 27899636. PubMed Central PMCID: PMC5210586.
Hochheiser H, Castine M, Harris D, Savova G, Jacobson RS. An information model for computable cancer phenotypes. BMC Medical Informatics and Decision Making. Sept. 2016: 1-15. doi=10.1186/s12911-016-0358-4.
Fisher A. Ding M, Hochheiser H, Douglas G. (2016) Measuring time utilization of pharmacists in the Birmingham Free Clinic dispensary. BMC Health Services Research 16(1-7) DOI: 10.1186/s12913-016-17. PMID: 27687973. PMCID: PMC5043635.
McMurry JA, Köhler S, Washington NL, Balhoff JP, Borromeo C, Brush M, Carbon S, Conlin T, Dunn N, Engelstad M, Foster E, Gourdine JP, Jacobsen JO, Keith D, Laraway B, Xuan JN, Shefchek K, Vasilevsky NA, Yuan Z, Lewis SE, Hochheiser H, Groza T, Smedley D, Robinson PN, Mungall CJ, Haendel MA. Navigating the Phenotype Frontier: The Monarch Initiative. Genetics. 2016 Aug;203(4):1491-5. PMID: 27516611 PMCID: PMC4981258.
Lazar J, Abascal J, Barbosa S, Barksdale J, Friedman B, Grossklags J, Gulliksen J, Johnson J, McEwan T, Martínez-Normand L, Michalk W, Tsai J, van der Veer G, von Axelson H, Walldius A, Whitney G, Winckler M, Wulf V, Churchill EF, Cranor L, Davis J, Hedge A, Hochheiser H, Hourcade JP, Lewis C, Nathan L, Paterno F, Reid B, Quesenbery W, Selker T, Wentz B. (2016), "Human–Computer Interaction and International Public Policymaking: A Framework for Understanding and Taking Future Actions", Foundations and Trends® Human–Computer Interaction: Vol. 9: No. 2, pp 69-149. http://dx.doi.org/10.1561/1100000062.
Hochheiser H, Ning Y, Hernandez A, Horn, JR, Jacobson R, Boyce RD. Using Nonexperts for Annotating Pharmacokinetic Drug-Drug Interaction Mentions in Product Labeling: A Feasibility Study. JMIR Res Protoc. 2016 Apr 11;5(2):e40. doi: 10.2196/resprot.5028. PMID: 27066806 PMCID: PMC4844909.
Romagnoli KM, Boyce RD, Empey PE, Adams S, Hochheiser H. Bringing clinical pharmacogenomics information to pharmacists: A qualitative study of information needs and resource requirements. Int J Med Inform. 2016 Feb;86:54-61. doi: 10.1016/j.ijmedinf.2015.11.015. Epub 2015 Nov 30. PMID: 26725696. PMCID: PMC4720137.
Cooper GF, Bahar I, Becich MJ, Benos PV, Berg J, Espino JU, Jacobson RC, Kienholz M, Lee AV, Lu X, Scheines R, Center for Causal Discovery team. The Center for causal discovery of biomedical knowledge from Big Data. J Am Med Inform Assoc. 2015 Nov;22(6): 1132-6. doi: 10.1093/jamia/ocv059. Epub 2015 Jul 2. PMID: 26138794. PMCID: PMC5009908.
Haendel MA, Vasilevsky N, Brush M, Hochheiser HS, Jacobsen J, Oellrich A, … Smedley D. (2015). Disease insights through cross-species phenotype comparisons. Mammalian Genome, 26(9-10), 548–555. http://doi.org/10.1007/s00335-015-9577-8 PMID: 26092691 PMCID: PMC4602072
Landis-Lewis Z, Douglas GP, Hochheiser H, Kam M, Gadabu O, Bwanali M, Jacobson RS. (2015). Computer-Supported Feedback Message Tailoring for Healthcare Providers in Malawi: Proof-of-Concept. AMIA Annual Symposium Proceedings, 2015, 814–823.
King AJ, Cooper GF, Hochheiser H, Clermont G. Development and preliminary evaluation of a prototype of a learning electronic medical record system. AMIA Annu Symp Proc. 2015 Nov 5;2015:1967-75. eCollection 2015. PMID: 26958296 PMCID: PMC4765593.
Strange C, Senior RM, Sciurba F, O'Neal S, Morris A, Wisniewski SR, Bowler R, Hochheiser HS, Becich MJ, Zhang Y, Leader JK, Methé BA, Kaminski N, Sandhaus RA; GRADS Alpha-1 Study Group. Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol. Ann Am Thorac Soc. 2015 Oct; 12(10): 1551-60. doi: 10.1513/AnnalsATS.201503-143OC. PMID: 26153726. PMCID: PMC4627425.
Mungall CJ, Washington NL, Nguyen-Xuan J, Condit C, Smedley D, Köhler S, Groza T, Shefchek K., Hochheiser H, Robinson PN, Lewis SE and Haendel MA. (2015), Use of Model Organism and Disease Databases to Support Matchmaking for Human Disease Gene Discovery. Human Mutation, 36: 979–984. doi:10.1002/humu.22857 PMID: 26269093
Landis-Lewis Z, Brehaut JC, Hochheiser H, Douglas GP, Jacobson RS. (2015). Computer-supported feedback message tailoring: theory-informed adaptation of clinical audit and feedback for learning and behavior change. Implementation Science. 2015 Jan 25; 10(12). doi: 10.1186/s13012-014-0203-z.
Ayvaz S, Zhu Q, Hochheiser H, Brochhausen M, Horn J, Dumontier M, … Boyce RD. (2014). Drug-Drug Interaction Data Source Survey and Linking. AMIA Summits on Translational Science Proceedings, 2014, 16. PMID: 25717393 PMCID: PMC4333686
Ligons FM, Mello-Thoms C, Handler SM, Romagnoli KM, Hochheiser H. (2014). Assessing the impact of cognitive impairment on the usability of an electronic medication delivery unit in an assisted living population. International Journal of Medical Informatics, 83(11), 841–848. http://doi.org/10.1016/j.ijmedinf.2014.07.004 PMID: 25153770 PMCID: PMC4268135
Wentz B, Hochheiser H, Lazar J. 2013. A survey of blind users on the usability of email applications. Univers. Access Inf. Soc. 12, 3 (August 2013), 327-336. DOI=http://dx.doi.org/10.1007/s10209-012-0285-9
Romagnoli KM, Handler SM, Ligons FM, Hochheiser H. Home-care nurses’ perceptions of unmet information needs and communication difficulties of older patients in the immediate post-hospital discharge period. BMJ quality & safety. 2013 Apr; 22 (4):324-32. PMCID: PMC3694324. PMID: 23362507.
Lazar J, Hochheiser H. Legal Aspects of Interface Accessibility in the U.S. Communications of the ACM. 2013 Dec; 56 (12):74-80.
Brinkley, J. F., Borromeo, C., Clarkson, M., Cox, T. C., Cunningham, M. J., Detwiler, L. T., … Shapiro, L. G. (2013). The Ontology of Craniofacial Development and Malformation for translational craniofacial research. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics, 0(4), 232–245. http://doi.org/10.1002/ajmg.c.31377 PMID: 24124010 PMCID: PMC4041627
Handler SM, Boyce RD, Ligons FM, Perera S, Nace DA, Hochheiser H. Use and Perceived Benefits of Mobile Devices by Physicians in Preventing Adverse Drug Events in the Nursing Home. Journal of The American Medical Directors Association. 2013 Oct 2. PMID: 24094901.
Osmanbeyoglu HU, Ganapathiraju MK. N-gram analysis of 970 microbial organisms reveals presence of biological language models. BMC Bioinformatics. 2011 Jan 10;12:12. doi: 10.1186/1471-2105-12-12. PubMed PMID: 21219653. PMCID: PMC3027111.
Hochheiser H, Shneiderman B. From Bowling Alone to Tweeting Together: Technology- Mediated Social Participation. interactions. 2010; 17(2):64-67. (Invited)
Lazar J, Feng J,Hochheiser H. Research Methods in Human-Computer Interaction. London: Wiley; 2010.
biomedical informatics; bioinformatics; clinical informatics; collaborative science; human-computer interaction; information visualization; computer-supported cooperative work; Attitude of Health Personnel; Humans; Workflow; Young Adult; Aged; Adult; Nursing Methodology Research; Qualitative Research;Nursing Staff, Hospital; Health Insurance Portability and Accountability Act; Nursing Evaluation Research; Point-of-Care Systems; United States; Male; Electronic Health Records; Nursing Records; Middle Aged